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Key Documents

SAB4700625

Sigma-Aldrich

Monoclonal Anti-CD24-PE antibody produced in rat

clone SN3, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-CD24

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.44

biological source

rat

Quality Level

100

conjugate

phycoerythrin (R-PE) conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

SN3, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

NM_013230.2

UniProt accession no.

P25063

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... CD24(100133941)

General description

Cluster of differentiation 24 (CD24) is a glycosylphosphatidylinositol-linked cell surface ligand for P-selectin. It is also expressed in the central nervous system. CD24 is located on human chromosome 6q21.

Immunogen

Glycoproteins purified from human NALM-1 cell line

Application

Monoclonal Anti-CD24-PE antibody has been used in fluorescence activated cell-sorting (FACS) analysis.

Biochem/physiol Actions

Cluster of differentiation 24 (CD24) is involved in neuronal development, intercellular signal transmission and immune regulation. This protein is linked with several autoimmune diseases, tumors and malignancies. It plays an important role in T-cell proliferation and lymphocyte maturation. CD24 also participates in self-renewal, proliferation and differentiation.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Comparison of stem cell behaviors between indigenous high and low-CD24 percentage expressing cells of stem cells from apical papilla (SCAPs).
Aguilar P and Lertchirakarn V
Tissue & cell, 48(5), 397-406 (2016)
CD24 expression may play a role as a predictive indicator and a modulator of cisplatin treatment response in head and neck squamous cellular carcinoma.
Modur V, et al.
PLoS ONE, 11(6), e0156651-e0156651 (2016)
Polymorphisms of the CD24 gene are associated with risk of multiple sclerosis: a meta-analysis.
Braliou GG, et al.
International Journal of Molecular Sciences, 16(6), 12368-12381 (2015)
Associations between CD24 gene polymorphisms and inflammatory bowel disease: A meta-analysis.
Huang XL, et al.
World Journal of Gastroenterology, 21(19), 6052-6052 (2015)
MiR-129 blocks estrogen induction of NOTCH signaling activity in breast cancer stem-like cells.
Xiao G, et al.
Oncotarget, 8(61), 103261-103261 (2017)
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