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C7020

Supelco

Cefadroxil

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C16H17N3O5S
CAS Number:
Molecular Weight:
363.39
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

form

powder or crystals

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C2=O)C(O)=O

InChI

1S/C16H17N3O5S/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24)/t10-,11-,15-/m1/s1

InChI key

BOEGTKLJZSQCCD-UEKVPHQBSA-N

General description

Cefadroxil is a broad spectrum cephalosporin antibiotic, widely used in veterinery medicine for the oral treatment of infectious diseases.

Application

Cefadroxil has been used as a standard in the analysis of cefadroxil residues in the samples of domestic sheep milk using penzym enzymatic test method. Cefadroxil may be used as an analytical reference standard for the quantification of the analyte in milk samples using Delvotest photometric technique and in biological samples using high-performance liquid chromatography, respectively.
Cefadroxil has been used as a standard in the analysis of cefadroxil residues in the samples of domestic sheep milk using penzym enzymatic test method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anil K Philip et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 658-666 (2008-01-22)
In the present study, both disintegrating and non-disintegrating polymeric capsular system in achieving delayed as well as improved osmotic flow for the model drug cefadroxil was developed. Asymmetric membrane in membrane capsule (AMMC) was prepared on a glass mold pin
Mohamed A Kamal et al.
Drug metabolism and pharmacokinetics, 23(4), 236-242 (2008-09-03)
Pept2 knockout mice are an important tool to evaluate the evolving role and relevance of this proton-coupled oligopeptide transporter beyond drug disposition, where the transporter also modulates the pharmacodynamic and toxicodynamic effects of drug substrates. Our in vivo studies with
DRESS syndrome from cefadroxil confirmed by positive patch test.
M Hernanto et al.
Allergy, 62(10), 1216-1217 (2007-06-21)
Generalized pustulosis.
Sudip Kumar Ghosh et al.
Indian pediatrics, 45(11), 934-935 (2008-11-26)
G Lamba et al.
The West Indian medical journal, 60(3), 346-348 (2012-01-10)
We report a life-threatening anaphylactic reaction to cefadroxil in a 60-year old female with no previous history of allergies to penicillins. Cefadroxil is a first-generation cephalosporin and anaphylactic reactions to it in patients with no previous history of penicillin allergy

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