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E1649

Sigma-Aldrich

Ethylenediamine

meets USP testing specifications

Synonym(s):

1,2-Diaminoethane

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About This Item

Linear Formula:
NH2CH2CH2NH2
CAS Number:
107-15-3
Molecular Weight:
60.10
Beilstein:
605263
EC Number:
203-468-6
MDL number:
MFCD00008204
UNSPSC Code:
12352116
PubChem Substance ID:
24894428
NACRES:
NA.25

Agency

USP/NF
meets USP testing specifications

Quality Level

200

vapor density

2.07 (vs air)

vapor pressure

10 mmHg ( 20 °C)

Assay

98.6% (Gew)

form

liquid

autoignition temp.

716 °F

expl. lim.

16 %

reaction suitability

reagent type: chelator

refractive index

n20/D 1.4565 (lit.)

bp

118 °C (lit.)

mp

8.5 °C (lit.)

solubility

H2O: soluble at 

density

0.899 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

NCCN

InChI

1S/C2H8N2/c3-1-2-4/h1-4H2

InChI key

PIICEJLVQHRZGT-UHFFFAOYSA-N

Gene Information

human ... FNTA(2339)

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 3 - Resp. Sens. 1B - Skin Corr. 1B - Skin Sens. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

100.4 °F - closed cup

Flash Point(C)

38 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCR0072
MKCT4360
MKCK8235
MKCF2814
MKBW9399V

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J Zuidema
Pharmaceutisch weekblad. Scientific edition, 7(4), 134-140 (1985-08-23)
Ethylenediamine is an excipient with many industrial and pharmaceutical uses. It is included in creams as a stabilizer and in aminophylline as the counter ion of theophylline. Ethylenediamine is one of the most frequent contact sensitizers, producing local and generalized
Ofra Benny et al.
Nature biotechnology, 26(7), 799-807 (2008-07-01)
Targeting angiogenesis, the formation of blood vessels, is an important modality for cancer therapy. TNP-470, a fumagillin analog, is among the most potent and broad-spectrum angiogenesis inhibitors. However, a major clinical limitation is its poor oral availability and short half-life
Maria V Babak et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 19(13), 4308-4318 (2013-01-24)
With the aim of systematically studying fundamental structure-activity relationships as a basis for the development of Ru(II) arene complexes (arene = p-cymene or biphenyl) bearing mono-, bi-, or tridentate am(m)ine ligands as anticancer agents, a series of ammine, ethylenediamine, and
Changhai Xu et al.
Carbohydrate polymers, 92(1), 249-253 (2012-12-12)
There exists a misunderstanding on the TAED-activated peroxide system in the textile industry that H(2)O(2) used in excess of the stoichiometric amount could produce an addition effect on bleaching of cotton under alkaline conditions. In this study, a critical reinvestigation
Mona Nystad et al.
American journal of obstetrics and gynecology, 211(6), 686-686 (2014-06-25)
The purpose of this study was to investigate the expression and subcellular localization of laeverin, a placenta-specific membrane-bound aminopeptidase, in preeclamptic placentas and its role in trophoblast cell migration and invasion. Expression of laeverin was investigated in 6 normal and
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