82815

Pyridinium p-toluenesulfonate

puriss., ≥99.0% (T)

• Synonym(s): p-Toluenesulfonic acid pyridine salt, PPTS, Pyridine p-toluenesulfonate
• Empirical Formula (Hill Notation): C₁₂H₁₃NO₃S
• CAS Number: 24057-28-1
• Molecular Weight: 251.30
• Beilstein: 3764305
• EC Number: 246-002-7
• MDL number: MFCD00013108
• UNSPSC Code: 12352106
• PubChem Substance ID: 329769266
• NACRES: NA.22

Properties

• grade: puriss.
• Quality Level: 200
• Assay: ≥99.0% (T)
• form: crystals
• mp: 117-120 °C
• SMILES string: c1ccncc1.Cc2ccc(cc2)S(O)(=O)=O
• InChI: 1S/C7H8O3S.C5H5N/c1-6-2-4-7(5-3-6)11(8,9)10;1-2-4-6-5-3-1/h2-5H,1H3,(H,8,9,10);1-5H
• InChI key: ZDYVRSLAEXCVBX-UHFFFAOYSA-N

Description

Application

Pyridinium p-toluenesulfonate is a mild and efficient catalyst for the formation and cleavage of acetals. This method has been adapted in the completely symmetric synthesis of tetrahydrolipstatin. It is also capable of selectively cleaving tert-butyldimethylsilyl (TBDMS) ethers in the presence of tert-butyldiphenlysilyl (TBDPS) ethers.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves