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Key Documents

AB9272

Sigma-Aldrich

Anti-Synaptophysin Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SYP(6855)

Specificity

Synaptophysin

Immunogen

Synthetic peptide from human synaptophysin.

Application

Anti-Synaptophysin Antibody detects level of Synaptophysin & has been published & validated for use in WB, IH(P).
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Western blot

Immunohistochemistry on formalin fixed, paraffin embedded tissue: 1:300 for 10 minutes at room temperature. Staining of formalin-fixed tissues requires boiling of tissues in 10 mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at room temperature for 20 minutes.

Optimal working dilutions must be determined by the end user.

STAINING PATTERN: Cytoplasmic

Linkage

Replaces: 04-1019

Physical form

Affinity purified immunoglobulin. Liquid in 10 mM PBS, pH 7.4 containing BSA and 0.1% sodium azide.

Storage and Stability

Maintain at 2-8°C for up to 6 months after date of receipt.

Analysis Note

Control
POSITIVE CONTROL: Pancreas or Pheochromocytoma

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Journal of Alzheimer's disease : JAD, 60(2), 549-560 (2017-09-05)
This study assessed the therapeutic utility of the autophagy enhancing stable disaccharide trehalose in the Tg2576 transgenic mouse model of Alzheimer's disease (AD) via an oral gavage of a 2% trehalose solution for 31 days. Furthermore, as AD is a
Scott D Z Eggers et al.
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Acta neuropathologica, 126(3), 329-352 (2013-07-04)
β-Site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) is the β-secretase that initiates Aβ production in Alzheimer's disease (AD). BACE1 levels are increased in AD, which could contribute to pathogenesis, yet the mechanism of BACE1 elevation is unclear. Furthermore, the

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