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1.00552

Supelco

ortho-Phosphoric acid

85%, Suprapur®

Synonym(s):

Phosphoric acid, o-Phosphoric acid, Orthophosphoric acid, Orthophosphoric acid

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About This Item

Linear Formula:
H3PO4
CAS Number:
Molecular Weight:
98.00
Beilstein:
1921286
MDL number:
UNSPSC Code:
12352301
NACRES:
NB.21

product name

ortho-Phosphoric acid 85%, Suprapur®

grade

for inorganic trace analysis

Quality Level

vapor density

3.4 (vs air)

vapor pressure

2.2 mmHg ( 20 °C)
5 mmHg ( 25 °C)

Assay

85%

form

liquid

pH

<0.5 (20 °C, 100 g/L in H2O)

kinematic viscosity

30.5 cSt(20 °C)

bp

158 °C (lit.)

mp

~40 °C (lit.)

density

1.685 g/mL at 25 °C (lit.)

storage temp.

no temp limit

SMILES string

OP(O)(O)=O

InChI

1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)

InChI key

NBIIXXVUZAFLBC-UHFFFAOYSA-N

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Application


  • Development of green micellar HPLC-DAD method for simultaneous determination of some sulbactam combinations used in COVID-19 regimen: This study presents a green analytical methodology utilizing micellar high-performance liquid chromatography with diode-array detection (HPLC-DAD). It is specifically employed for the simultaneous determination of sulbactam and other compounds in COVID-19 treatment regimens, showcasing an application of ortho-Phosphoric acid in adjusting the pH of the mobile phase to enhance analytical performance and separation efficiency (Ragab GH, Saleh HM, Abdulla NM, Bahgat EA, 2023).

Other Notes

Concentrated phosphoric acid is approx. 85% H3PO4 (aqueous).

Linkage

Replaces: 552; 552-2; 552-3

Analysis Note

Assay (acidimetric): ≥ 85.0 %
Chloride (Cl): ≤ 500 ppb
Fluoride (F): ≤ 500 ppb
Nitrate (NO₃): ≤ 500 ppb
Sulphate (SO₄): ≤ 10 ppm
Ag (Silver): ≤ 20 ppb
Al (Aluminium): ≤ 20 ppb
As (Arsenic): ≤ 25 ppb
Au (Gold): ≤ 20 ppb
Ba (Barium): ≤ 20 ppb
Be (Beryllium): ≤ 50 ppb
Bi (Bismuth): ≤ 50 ppb
Ca (Calcium): ≤ 50 ppb
Cd (Cadmium): ≤ 20 ppb
Co (Cobalt): ≤ 20 ppb
Cr (Chromium): ≤ 50 ppb
Cu (Copper): ≤ 25 ppb
Fe (Iron): ≤ 200 ppb
Hg (Mercury): ≤ 2 ppb
K (Potassium): ≤ 50 ppb
Li (Lithium): ≤ 20 ppb
Mg (Magnesium): ≤ 20 ppb
Mn (Manganese): ≤ 20 ppb
Mo (Molybdenum): ≤ 20 ppb
Na (Sodium): ≤ 100 ppb
Ni (Nickel): ≤ 25 ppb
Pb (Lead): ≤ 20 ppb
Pt (Platinum): ≤ 100 ppb
Sb (Antimony): ≤ 800 ppb
Sn (Tin): ≤ 50 ppb
Sr (Strontium): ≤ 20 ppb
Tl (Thallium): ≤ 20 ppb
V (Vanadium): ≤ 20 ppb
Zn (Zinc): ≤ 25 ppb
Zr (Zirconium): ≤ 50 ppb
The actual values are subject to unavoidable systematic
variations in this concentration range.

Legal Information

SUPRAPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 1


Certificates of Analysis (COA)

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Articles

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Control elemental impurities in drug products with analytical methods and materials to ensure patient safety.

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