Skip to Content
Merck
All Photos(1)

Documents

194395

Sigma-Aldrich

1,3-Dibromobenzene

97%

Synonym(s):

1-Bromo-3-bromobenzene, m-Dibromobenzene

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C6H4Br2
CAS Number:
108-36-1
Molecular Weight:
235.90
Beilstein:
1904538
EC Number:
203-574-2
MDL number:
MFCD00000078
UNSPSC Code:
12352100
PubChem Substance ID:
24851649
NACRES:
NA.22

vapor density

8.16 (vs air)

vapor pressure

5 mmHg ( 66 °C)

Assay

97%

form

liquid

refractive index

n20/D 1.608 (lit.)

bp

218-219 °C (lit.)

mp

−7 °C (lit.)

density

1.952 g/mL at 25 °C (lit.)

SMILES string

Brc1cccc(Br)c1

InChI

1S/C6H4Br2/c7-5-2-1-3-6(8)4-5/h1-4H

InChI key

JSRLURSZEMLAFO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

1,3-Dibromobenzene undergoes solid-supported [KF-Al2O3] palladium-catalyzed polyarylation reaction with phenyl boronic acid under microwave irradiation to yield conjugated polyaryls.

Application

1,3-Dibromobenzene was used in the synthesis of [n]metacyclophanes via Suzuki coupling reaction.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

200.1 °F - closed cup

Flash Point(C)

93.4 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Microwave-assisted Suzuki coupling on a KF-alumina surface: synthesis of polyaryls. Microwave-assisted Suzuki coupling on a KF-alumina surface: synthesis of polyaryls.
Basu B, et al.
Tetrahedron Letters, 44(19), 3817-3820 (2003)
Beverly B Smith et al.
The Journal of organic chemistry, 67(15), 5333-5337 (2002-07-20)
Reaction of the bis-9-BBN adduct of several dienes with 1,3-dibromobenzene via Suzuki coupling leads to a series of [n]metacyclophanes ranging in size from 10 to 17 atom members. In each case, two carbon-carbon bonds are formed in one reaction vessel.
J A Szymańska
Archives of toxicology, 71(1-2), 99-106 (1996-01-01)
Rats were used to study acute and subacute hepatotoxicity of 1,3-dibromobenzene (1,3-dBB). In the single-exposure experiment, maximum hepatic 1,3-dBB concentrations were found to occur 1 to 12 h after the exposure, depending on the dose. Maximum concentrations of covalently bound
A Sapota et al.
Chemosphere, 39(13), 2229-2238 (1999-11-27)
The distribution, excretion and metabolism of 1,3-dibromobenzene following a single i.p. administration to rats 100 or 300 mg/kg was investigated using radiotracer [3H] and GC-MS technique. After 72 hours about 74 to 90% were excreted in urine. The highest radioactivity
J A Szymańska et al.
Journal of applied toxicology : JAT, 16(1), 35-41 (1996-01-01)
Various doses of dibromobenzene isomers (1,2-dBB, 1,3-dBB, 1,4-dBB) were administered (i.p.) to BALB mice. The levels of reduced glutathione (GSH) and malondialdehyde (MDA) in the liver, and glutamate-pyruvate transaminase (GPT) (EC.2.6.1.2) gamma-glutamyltransferase (gamma-GT) (EC.2.3.2.2) and triglycerides (TG) in the serum
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service