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D-Biotin

analytical standard

Synonym(s):

Biotin, D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H

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About This Item

Empirical Formula (Hill Notation):
C10H16N2O3S
CAS Number:
Molecular Weight:
244.31
Beilstein:
86838
EC Number:
MDL number:
UNSPSC Code:
12164500
PubChem Substance ID:

grade

analytical standard

feature

standard type water soluble vitamin

packaging

ampule of 100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

231-233 °C (lit.)

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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General description

D-biotin is water soluble vitamin, which belongs to the B-complex group of vitamins. It generally serves as a covalently-bound coenzyme for several carboxylases. It is an essential micronutrient required for normal cell functions and can be obtained both dietary sources as well as gut microbiota.

Application

D-Biotin may be used as an analytical reference standard for the quantification of the analyte in food samples using high-performance liquid chromatography (HPLC)/avidin-binding assay.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Pharmacological Effects of Biotin in Animals
L R-N and C F-M
Mini-Reviews in Medicinal Chemistry, 17, 529-529 (2017)
Lipopolysaccharide inhibits colonic biotin uptake via interference with membrane expression of its transporter: a role for a casein kinase 2-mediated pathway
Lakhan R and Said.MS
American Journal of Physiology. Cell Physiology, 312, C376-C384 (2017)
Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding
Staggs GC, et al.
Journal of food composition and analysis, 17(6), 767-776 (2004)
Naruo Nikoh et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(28), 10257-10262 (2014-07-02)
Obligate insect-bacterium nutritional mutualism is among the most sophisticated forms of symbiosis, wherein the host and the symbiont are integrated into a coherent biological entity and unable to survive without the partnership. Originally, however, such obligate symbiotic bacteria must have
Tuan V Bui et al.
Neuron, 78(1), 191-204 (2013-04-16)
Accurate motor performance depends on the integration in spinal microcircuits of sensory feedback information. Hand grasp is a skilled motor behavior known to require cutaneous sensory feedback, but spinal microcircuits that process and relay this feedback to the motor system

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