47783

(±)-α-Tocopherol

analytical standard

• Synonym(s): DL-all-rac-α-Tocopherol, Vitamin E
• Empirical Formula (Hill Notation): C₂₉H₅₀O₂
• CAS Number: 10191-41-0
• Molecular Weight: 430.71
• Beilstein: 94012
• EC Number: 233-466-0
• MDL number: MFCD00006848
• UNSPSC Code: 12164500
• PubChem Substance ID: 24871420
• E Number: E307

Properties

• grade: analytical standard
• form: liquid
• CofA: current certificate can be downloaded
• feature: standard type fat soluble vitamin
• packaging: ampule of 100 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• density: 0.950 g/mL at 20 °C (lit.)
• application(s): food and beverages
• format: neat
• storage temp.: -10 to -25°C
• SMILES string: CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1
• InChI: 1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
• InChI key: GVJHHUAWPYXKBD-UHFFFAOYSA-N

Description

General description

α-Tocopherol is a form of fat-soluble vitamin E and shows anti-oxidant, anti-inflammatory, anti-cell proliferative, and anti-cancer properties.

This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

The analytical standard can also be used as follows:

• Simultaneous determination of vitamin A and all four tocopherol isomers in human serum samples by ultra-high performance liquid chromatography (UHPLC) combined with fluorescence detection following their liquid-liquid extraction (LLE)
• Multi-residue analysis of vitamin B (B₁, B₂, B₅, and B₉), and vitamin E (α-tocopherol, β-tocopherol, α-tocotrienol, and β-tocotrienol) in grass and grain samples of four different wheat varieties by liquid chromatography-electrospray ionization/multistage mass spectrometry (LC-ESI-MS/MS)
• Separation and estimation of four tocopherols and four tocotrienols in pecan nut cultivar samples using non-aqueous reversed-phase high-performance liquid chromatography (NARP-HPLC) coupled with atmospheric pressure chemical ionization-tandem mass spectrometric (APCI-MS/MS) detection
• Analysis of different cold pressed oil samples to detect and quantify eight tocol- homologs using a chemometrically-assisted optimized high-performance liquid chromatography (HPLC) with fluorescence detection (FLD) based method
• Multi-residue determination of tocopherols in aromatic peanut oil (APO) and four refined vegetable oils using high-performance liquid chromatography with UV detection to detect adulteration

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P333 + P313 - P362 + P364 - P501
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves