SML3437
Epigoitrin
≥98% (HPLC)
Synonym(s):
(+)-5-Vinyl-2-oxazolidinethione, (5R)-5-ethenyl-1,3-oxazolidine-2-thione, (R)-goitrin, CID 3032313, D-Goitrin
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About This Item
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Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Epigoitrin is a sulfur containing alkaloid isolated from Isatis indigotica (Ban Lan Gen) that exhibits antiviral, anticancer, and antithyroid activities. Epigoitrin significantly decreases the susceptibility of restraint mice to H1N1 influenza virus. Epigoitrin and goitrin appear to show virucidal effect on influenza virus A (H1N1) in vitro and in ovo.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
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Journal of ethnopharmacology, 251, 112550-112550 (2020-01-10)
Isatidis Radix, the sun-dried roots of Isatis indigotica Fortune ex Lindl., is one of the most usually used traditional Chinese medicines. For centuries, the herb has been employed in clinical practice for treatment of virus infection and inflammation. However, its
Frontiers in pharmacology, 10, 78-78 (2019-02-23)
Stress has been proven to modulate an individual's immune system through the release of pituitary and adrenal hormones such as the catecholamines, growth hormone, and glucocorticoids. These signal molecules can significantly alter the host immune system and make it susceptible
Journal of analytical methods in chemistry, 2017, 2810565-2810565 (2017-09-13)
Radix isatidis (Banlangen) is a widely used traditional Chinese medicine for treating fever and removing toxic heat. Pharmacological studies have indicated that (R)-goitrin (epigoitrin) is one of the main constituents accounting for its antiviral activity, while (S)-goitrin (goitrin) is known
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