SAB4504315

Anti-phospho-PI3-kinase p85-α (pTyr⁶⁰⁷) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-AGM7, Anti-GRB1, Anti-IMD36, Anti-p85, Anti-p85-ALPHA
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 83 kDa
• species reactivity: human, mouse, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P27986
• UniProt accession no.: P27986
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr607)
• Gene Information: human ... PIK3R1(5295)

Description

General description

PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is a pleiotropic gene, that codes for a p85α regulatory subunit of phosphatidylinositol-3 kinase (PI3K). This gene is mapped to human chromosome 5q13.

Immunogen

The antiserum was produced against synthesized peptide derived from human PI3-kinase p85-alpha around the phosphorylation site of Tyr607.

Immunogen Range: 573-622

Biochem/physiol Actions

PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is known to mediate immune cell differentiation, development and function. Mutations in PIK3R1 gene result in SHORT syndrome, hyper IgM syndrome, lymphadenopathy and short stature.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable