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S2770

Sigma-Aldrich

Sodium hydroxide solution

1.0 N, BioReagent, suitable for cell culture

Synonym(s):

Caustic Soda, Lye, NaOH, Soda

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About This Item

Linear Formula:
NaOH
CAS Number:
1310-73-2
Molecular Weight:
40.00
MDL number:
MFCD00003548
UNSPSC Code:
12352316
PubChem Substance ID:
24899535
NACRES:
NA.71
Pricing and availability is not currently available.

vapor pressure

3 mmHg ( 37 °C)

Quality Level

200

sterility

sterile-filtered

product line

BioReagent

form

solution

concentration

1.0 N

technique(s)

cell culture | mammalian: suitable

SMILES string

[OH-].[Na+]

InChI

1S/Na.H2O/h;1H2/q+1;/p-1

InChI key

HEMHJVSKTPXQMS-UHFFFAOYSA-M

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General description

Sodium hydroxide is a strong alkali. Its reaction with acid yields salt and water. Sodium hydroxide solution has many industrial applications including dyes and drugs. It has the ability to disintegrate lignin and hence is used in paper manufacturing. Sodium hydroxide has high melting of about 318°C.[1]

Application

Sodium hydroxide solution has been used:
  • to neutralize collagen type I solution phosphate-buffered saline for its use in 3D cell culture technique[2]
  • to dissolve phosphate chains in phosphate glass for optical characterisation[3]
  • as a component of transfer medium used for cell culture[4]
  • as a general titration base for cell culture applications.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H290,H314

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
RNBL6715
RNBL4710
RNBL4177
RNBL3666
RNBL2228

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Isolation and culture of human endometrial epithelial cells and stromal fibroblasts
Chen JC and Roan NR
Bio-protocol, 5(20) (2015)
Matrix dimensions, stiffness, and structural properties modulate spontaneous chondrogenic commitment of mouse embryonic fibroblasts
Fernandez MT
Tissue Engineering: Part A, 20(7-8), 1145-1155 (2013)
Sodium, 21-21 (2002)
Optical characterisation of hydroxide catalysed bonds applied to phosphate glass
Optifab, 10448, 1044825-1044825 (2017)
Konstantinos A Polyzos et al.
Cardiovascular research, 106(2), 295-302 (2015-03-10)
Atherosclerosis is a chronic inflammatory disease that is initiated by the retention and accumulation of low-density lipoprotein in the artery, leading to maladaptive response of cells from the immune system and vessel wall. Strong evidence implicates indoleamine 2,3-dioxygenase (IDO), the
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Questions

1–4 of 4 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Is this product Molecular Biology Grade?

    1 answer

    1. This product has been tested for use in Cell Culture applications and would not be considered a Molecular Biology grade item. Product 72068, Sodium Hydroxide BioUltra for Molecular Biology may be of interest. This product is only available at a 10M concentration. Please see the link below to review this product option:
      https://www.sigmaaldrich.com/product/sigma/72068

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  4. How do we determine the expiry date for this product. We have a lot Number RMBL3666.

    1 answer

    1. The lot number RMBL3666 does not exist as a valid lot under this product number. The correct lot number is RNBL3666. This product does not contain an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services

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