M9557
Anti-Macrophage Inflammatory Protein-3β antibody produced in goat
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-MIP-3β
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About This Item
Recommended Products
biological source
goat
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
mouse
technique(s)
immunocytochemistry: 5-15 μg/mL
neutralization: 0.8-4 μg/mL
western blot: 0.1-0.2 μg/mL
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Ccl19(24047)
General description
The antibody neutralizes the biological activity of recombinant mouse MIP-3β. Using 50 times more, the antibody will neutralize the biological activity of recombinant human MIP-3β. The antibody shows 5% cross-reactivity with recombinant human MIP-3β.
Immunogen
Recombinant mouse MIP-3β, expressed in Escherichia coli.
Biochem/physiol Actions
Macrophage Inflammatory Protein-3β is a chemokine that facilitates the migration of dendritic cells and antigen-presenting cells. It interacts with specific G protein-coupled seven-transmembrane domain chemokine receptor, CCR7 and promotes interactions between T cells and dendritic cells and migration of activated B cells to lymphoid tissues.
Physical form
Lyophilized from a 0.2 μm-filtered solution in phosphate-buffered saline containing carbohydrates.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Jian-mei Hou et al.
Acta pharmacologica Sinica, 30(3), 355-363 (2009-03-06)
Tumor immunotherapy aims at activating the body's own immune system to fight an existing tumor. Effective antitumor responses require tumor antigens to be presented to lymphocytes. We aimed to test the hypothesis that intratumoral administration of recombinant adenovirus encoding MIP3beta
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