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pH
7.4-8.8
pKa (25 °C)
8.1
pKa (20 °C)
8.20
SMILES string
Cl.NCC(N)=O
InChI
1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H
InChI key
WKNMKGVLOWGGOU-UHFFFAOYSA-N
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Product No.
Description
Pricing
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Biochemistry, 46(13), 4037-4044 (2007-03-14)
As a model for mechanistic comparison with peptidyl transfer within the ribosome, the reaction of aqueous glycinamide with N-formylphenylalanine trifluoroethyl ester (fPhe-TFE) represents an improvement over earlier model reactions involving Tris. The acidity of trifluoroethanol (pKa 12.4) resembles that of
The Journal of organic chemistry, 78(18), 9450-9456 (2013-08-21)
A catalytic α-sp(3) C-H oxidation of peptides and glycine amides was achieved under radical cation salt catalysis in the presence of O2, producing a series of substituted quinolines. The scope of this reaction shows good functional group tolerance and high
Analytical chemistry, 79(14), 5382-5391 (2007-05-29)
When mobile-phase salt content is increased, cationic analytes often show increased retention. This effect is generally attributed to chaotropic or ion pairing effects. However, a cation exclusion mechanism could explain the same effects. In this study, experimental conditions were manipulated
Bioorganic & medicinal chemistry letters, 20(8), 2425-2430 (2010-03-30)
We describe the design, synthesis, and evaluation, of gamma-lactams as glycinamide replacements within a series of di- and trisubstituted cyclohexane CCR2 antagonists. The lactam-containing trisubstituted cyclohexanes proved to be more potent than the disubstituted analogs, as trisubstituted analog, lactam 13
Journal of medicinal chemistry, 48(24), 7808-7820 (2005-11-24)
4-(Phenylamino)-5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine 1 and related compounds known as "diaryltubercidin" analogues are potent inhibitors of adenosine kinase (AK) and are orally active in animal models of pain such as the rat formalin paw model (GP3269 ED50= 6.4 mg/kg). However, the utility of
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