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About This Item
Empirical Formula (Hill Notation):
C22H26N2O5S
CAS Number:
Molecular Weight:
430.52
MDL number:
UNSPSC Code:
12352200
storage temp.
2-8°C
SMILES string
CSCCC(NC(=O)C(Cc1ccccc1)NC(=O)OCc2ccccc2)C(O)=O
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Pepstatin A-induced degranulation and superoxide anion generation by human neutrophils.
R J Smith et al.
Clinical immunology and immunopathology, 22(1), 83-93 (1982-01-01)
G Marone et al.
Agents and actions, 16(5), 306-309 (1985-07-01)
Pepstatin A, a pentapeptide isolated from cultures of actinomycetes, induced histamine secretion from human basophils in the concentration range of 3 X 10(-7) to 10(-4) M. The characteristics of this reaction were similar to those of f-met-peptide-induced histamine release: pepstatin
[Synthesis of dipeptide derivatives of indomethacin as potential antagonists of chemotactic compounds].
J Kolwas et al.
Acta poloniae pharmaceutica, 41(5), 541-546 (1984-01-01)
D C Rayner et al.
Cancer research, 45(5), 2288-2293 (1985-05-01)
N-Formylmethionylleucylphenylalanine (fMLP) induces chemotaxis in leukocytes, the response being mediated by peptide binding to a receptor on the plasma membrane. In tumor cells, this peptide has been reported to induce cellular swelling and chemotaxis in vitro and to enhance the
J D Williams et al.
Journal of immunology (Baltimore, Md. : 1950), 136(2), 642-648 (1986-01-01)
The N-formylated tripeptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) initiated the generation of immunoreactive C-6 sulfidopeptide leukotrienes and of leukotriene B4 (LTB4) in a dose-dependent manner from monolayers of human monocytes pretreated for 10 min with 5 micrograms/ml of cytochalasin B. The EC50 for
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