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A8171

Sigma-Aldrich

D-Ala-Leu-Lys-7-amido-4-methylcoumarin

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C25H37N5O5
CAS Number:
104881-72-3
Molecular Weight:
487.59
MDL number:
MFCD00038827
UNSPSC Code:
12352204
PubChem Substance ID:
24891207
NACRES:
NA.32

Assay

≥95% (HPLC)

form

powder

solubility

water: 1 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C(C)N)C(=O)NC(CCCCN)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C25H37N5O5/c1-14(2)11-20(30-23(32)16(4)27)25(34)29-19(7-5-6-10-26)24(33)28-17-8-9-18-15(3)12-22(31)35-21(18)13-17/h8-9,12-14,16,19-20H,5-7,10-11,26-27H2,1-4H3,(H,28,33)(H,29,34)(H,30,32)

InChI key

FHYIXLQAMONDNN-UHFFFAOYSA-N

Substrates

Fluorogenic substrate for plasmin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Direct photometric or fluorometric assay of proteinases using substrates containing 7-amino-4-trifluoromethylcoumarin.
R E Smith et al.
Thrombosis research, 17(3-4), 393-402 (1980-02-01)
María D Valls et al.
Frontiers in pharmacology, 12, 654104-654104 (2021-05-15)
Adenosine A2A receptor mediates the promotion of wound healing and revascularization of injured tissue, in healthy and animals with impaired wound healing, through a mechanism depending upon tissue plasminogen activator (tPA), a component of the fibrinolytic system. In order to

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