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A6414

Sigma-Aldrich

Albumin from rat serum

lyophilized powder, essentially fatty acid free, essentially globulin free, ≥99% (agarose gel electrophoresis)

Synonym(s):

RSA, Rat albumin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.27

biological source

rat

Assay

≥99% (agarose gel electrophoresis)

form

lyophilized powder

technique(s)

ELISA: suitable
tissue culture: suitable
western blot: suitable

UniProt accession no.

storage temp.

2-8°C

Gene Information

rat ... ALB(24186)

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General description

Albumin is the most abundant plasma protein in humans. Albumin turnover is seen in infants with iron deficiency anemia. Serum albumin is a reliable prognostic indicator for liver disease. Oxidative damage of albumin is associated with advanced liver disease.

Application

Albumin from rat serum has been used:
  • to study its sequence information from multiply charged ions formed by electrospray ionization
  • to cross-link with silk fibroin (SF) to synthesize a combined protein template
  • to infused into the brain to study its effects on nerve cell damage following brain injury

Preparation Note

Prepared from essentially globulin free albumin (A4538).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tandem mass spectrometry of very large molecules: serum albumin sequence information from multiply charged ions formed by electrospray ionization
Loo JA, et al.
Analytical Chemistry, 63(21), 2488-2499 (1991)
Chimeric protein template-induced shape control of bone mineral nanoparticles and its impact on mesenchymal stem cell fate
Wang J, et al.
Biomacromolecules, 16(7), 1987-1996 (2015)
Erica Polo-Hernández et al.
Journal of neurochemistry, 114(6), 1756-1766 (2010-07-16)
Our previous works showed that oleic acid synthesized in vitro by astrocytes in response to albumin behaves as a neurotrophic factor in neurons, up-regulating several proteins, such as the axonal growth marker growth-associated protein 43(GAP-43). Although the molecular mechanism of
Is calcium accumulation post-injury an indicator of cell damage?
Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma, 15-20 (1996)
Anne Skøttrup Mørkholt et al.
Scientific reports, 8(1), 7092-7092 (2018-05-08)
Multiple sclerosis (MS) is a neurodegenerative autoimmune disease, where chronic inflammation plays an essential role in its pathology. A feature of MS is the production of autoantibodies stimulated by an altered-peptide-ligand response and epitope spreading, resulting in loss of tolerance

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