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90771

Sigma-Aldrich

Poly(maleic anhydride-alt-1-tetradecene), 3-(dimethylamino)-1-propylamine derivative

BioReagent, for molecular biology

Synonym(s):

PMAL®-C12

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About This Item

Linear Formula:
(C23H44O3N2)n
CAS Number:
869857-14-7
UNSPSC Code:
12352200
NACRES:
NA.25
Pricing and availability is not currently available.

grade

Molecular Biology
for molecular biology

description

zwitterionic

product line

BioReagent

form

solid

λ

0.1 % in H2O

UV absorption

λ: 260 nm Amax: 0.400
λ: 280 nm Amax: 0.150

storage temp.

−20°C

Application

Use of "Amphipols" for delivering of membrane proteins to lipid bilayers[1], as activity support of membrane enzymes[2].

Analysis Note

enzyme traces DNases, RNases, and phosphatases not detectable

Legal Information

PMAL is a registered trademark of Affymetrix, Inc.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC2185
BCBZ3595
BCBJ5460V
BCBQ6755V
BCBJ5809V

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3-(Dimethylamino)-1-propylamine 99%

Sigma-Aldrich

D145009

3-(Dimethylamino)-1-propylamine

J K Nagy et al.
FEBS letters, 501(2-3), 115-120 (2001-07-27)
Data are presented which suggest that a class of amphiphilic polymers known as 'amphipols' may serve as a vehicle for delivering complex integral membrane proteins into membranes. The integral membrane protein diacylglycerol kinase (DAGK) was maintained in soluble form by
Bonnie M Gorzelle et al.
Journal of the American Chemical Society, 124(39), 11594-11595 (2002-09-26)
Amphipathic polymers ("amphipols") were introduced several years ago (Tribet, C.; Audebert, R.; Popot, J.-L. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 15047-15050) as an alternative method for solubilizing integral membrane proteins in stable, nativelike conformations. However, direct maintenance of full

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