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62650

Sigma-Aldrich

Lugol solution

for microscopy (Bact., Bot.)

Synonym(s):

Iodine/Potassium iodide solution

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About This Item

MDL number:
MFCD00134128
UNSPSC Code:
12171500
PubChem Substance ID:
329759746
NACRES:
NA.47
Pricing and availability is not currently available.

grade

for microscopy (Bact., Bot.)

Quality Level

200

technique(s)

microbe id | staining: suitable

density

1.007 g/mL at 20 °C

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

suitability

protozoa

SMILES string

[K+].[I-].II

InChI

1S/I2.HI.K/c1-2;;/h;1H;/q;;+1/p-1

InChI key

XUEKKCJEQVGHQZ-UHFFFAOYSA-M

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General description

Lugol iodine solution is an effective preservative for the marine bacteria.[1]
Lugol solution is a disinfectant, which is used to detect starch in organic compounds. It is used in dental procedures, diagnosis of cervical cell alterations and Schiller´s test.[2] Lugol solution is used in panendoscopic examination of squamous cell carcinoma of the esophagus.[3] It is used as a mordant in Gram staining.[4]

Application

Lugol solution has been used as a staining component to detect starch in plants.[5][6][7] It has also been used to saturate thyroid in biodistribution study.[8]

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM7251
BCCK7440
BCCH5982
BCCG9987
BCCG9986

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The Chemical Mechanism of Bacterial Behavior: I. Behavior Toward Dyes-Factors Controlling the Gram Reaction 1
Stearn EW and Stearn AE
Journal of Bacteriology, 9(5), 463-463 (1924)
Evaluation of the presence of arabinogalactan proteins and pectins during Quercus suber male gametogenesis
Costa M, et al.
Annals of Botany, 115(1), 81-92 (2014)
A J Pomroy
Applied and environmental microbiology, 47(5), 1191-1192 (1984-05-01)
Lugol iodine solution was compared with glutaraldehyde as a preservative for marine bacteria. Direct counts with the fluorochrome 4',6-diamidino-2-phenylindole show no significant difference between the preservatives, but the use of Lugol solution has several advantages over glutaraldehyde, especially in the
Cryo-focused ion beam sample preparation for imaging vitreous cells by cryo-electron tomography
Schaffer M, et al.
Bio-protocol, 5.17, e1575-e1575 (2015)
Yeşim Erbil et al.
The Journal of clinical endocrinology and metabolism, 92(6), 2182-2189 (2007-03-29)
Although some endocrine surgeons administer Lugol solution to decrease thyroid gland vascularity, there is still not an agreement on its effectiveness. The aims of this clinical trial are to evaluate thyroid blood flow and microvessel density in patients with Graves'
View All Related Papers

Questions

1–6 of 6 Questions  

  1. 欧州薬局方の試験に使用可能な試薬であるかご教授ください。 使用不可の場合は、貴社のルゴール溶液で、使用可能な別の商品がございましたら、ご案内をお願いいたします。

    1 answer

    1. This product is not a certified primary or secondary European Pharmacopoeia reference standard and is intended for Research Use Only. A review of various popular agencies - USP, BP, JP, NIST – reveals that currently, there are no primary standards for this material available. Please see the link below to review all of the current Lugol Solution product options. The end user would have to determine suitability based on the specific application or protocol:
      https://www.sigmaaldrich.com/US/en/search/lugol?focus=products&page=1&perpage=30&sort=relevance&term=lugol&type=product

      Helpful?

  2. Is this product (62650) acidic Lugol's solution, meaning does this product contain acid? 

    1 answer

    1. This product does not contain acid. Modification with acetic acid will have to be done by the user.

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  3. Can Lugol Solution (62650) be used as a contrast-enhancing agent?

    1 answer

    1. Lugol Solution (62650) is commonly associated with use in various Gram Stain Procedures. It can also be used for identifying parasites in feces or other biological specimens. Additionally, it is sometimes used for the detection of cervical cancer, but more concentrated solutions are typically used for this purpose.

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  4. What are the concentrations of iodine and potassium iodide in the liter of Lugol solution (product 62650)?

    1 answer

    1. The concentrations of iodine and potassium iodide in the liter of Lugol solution (product 62650) fall within the range of 0.33% - 0.37% for iodine and 0.67% - 0.71% for potassium iodide. The exact composition of each lot is considered proprietary.

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  5. Does this lugol's solution contain 0.35% iodine or 35% iodine?

    1 answer

    1. This Lugol's solution contains 0.35% iodine.

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  6. What is the concentration? Is it a ready-to-use solution?

    1 answer

    1. This product is formulated to contain approximately 0.35% Iodine and 0.70% Potassium Iodide. Product L6146, a similar Lugol solution, is a bit higher at 0.37% Iodine and 0.74% Potassium Iodide,

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