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Supelco

Decoquinate

VETRANAL®, analytical standard

Synonym(s):

Ethyl 6-decyloxy-7-ethoxy-4-hydroxy-3-quinolinecarboxylate

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About This Item

Empirical Formula (Hill Notation):
C24H35NO5
CAS Number:
Molecular Weight:
417.54
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCCCCCCCCCOc1cc2c(O)c(cnc2cc1OCC)C(=O)OCC

InChI

1S/C24H35NO5/c1-4-7-8-9-10-11-12-13-14-30-21-15-18-20(16-22(21)28-5-2)25-17-19(23(18)26)24(27)29-6-3/h15-17H,4-14H2,1-3H3,(H,25,26)

InChI key

JHAYEQICABJSTP-UHFFFAOYSA-N

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General description

Decoquinate is a quinolone coccidiostat used in poultry, to retard the growth of coccidian parasites and can also show activity against Plasmodium falciparum parasite, which causes malaria in humans.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor
Nam T-G, et al.
ACS Chemical Biology, 6, 1214-1222 (2011)
Medicating feeds for early lambing ewes.
Neville Suttle
The Veterinary record, 170(6), 161-161 (2012-02-15)
Cytochrome b mutation identified in a decoquinate-resistant mutant of Toxoplasma gondii.
D C McFadden et al.
The Journal of eukaryotic microbiology, 46(5), 81S-82S (1999-10-16)
D S Lindsay et al.
Veterinary parasitology, 89(4), 307-311 (2000-05-09)
Cryptosporidium parvum is an apicomplexan parasite that is an important cause of diarrhea in neonatal calves and humans. No treatment is currently available for neonatal calves. We have recently learned from colleagues in the pharmaceutical industry that dairy practitioners are
D S Lindsay et al.
Veterinary parasitology, 68(1-2), 35-40 (1997-01-01)
Neospora caninum is a major cause of abortion in dairy cattle in the United States and other countries. Abortions and neonatal mortality also occur in other ruminant species. Decoquinate is an anticoccidial that is approved for use in cattle and

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