31707
Dimetridazole
VETRANAL®, analytical standard
Synonym(s):
1,2-Dimethyl-5-nitroimidazole
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About This Item
Empirical Formula (Hill Notation):
C5H7N3O2
CAS Number:
Molecular Weight:
141.13
Beilstein:
130665
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
Cc1ncc(n1C)[N+]([O-])=O
InChI
1S/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3
InChI key
IBXPYPUJPLLOIN-UHFFFAOYSA-N
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General description
Dimetridazole (DMZ) is a 5-nitroimidazole type veterinary drug mostly used for treating infections caused by bacteria and protozoa. These infections can be frequently seen in the poultry industry.
Application
Dimetridazole has been used as reference standard for determination of DMZ concentration from poultry muscles, porcine kidney and liver, and chicken liver tissues using gas chromatography–electron capture negative ionization mass spectrometry (GC–ECNI-MS).
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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Determination of dimetridazole and metronidazole in poultry and porcine tissues by gas chromatography?electron capture negative ionization mass spectrometry.
Ho, Clare, et al.
Analytica Chimica Acta, 530.1, 23-31 (2005)
Harold M J F van der Heijden et al.
Avian pathology : journal of the W.V.P.A, 37(1), 45-50 (2008-01-19)
Histomoniasis is a serious disease in poultry. All chemotherapeutics with known efficacy against its causative agent, Histomonas meleagridis, have been banned from use as prophylactic or therapeutic use in production animals. In a search for possible alternatives, the in vivo
M P Callait et al.
Poultry science, 81(8), 1122-1127 (2002-09-05)
Histomoniasis or blackhead is a life-threatening disease of turkeys that is caused by a flagellated protozoan, Histomonas meleagridis. The development of an assay to measure the sensitivity of drugs traditionally used against this parasite, as reputed to be effective against
M Sánchez-Polo et al.
Water research, 43(16), 4028-4036 (2009-06-23)
The main objectives of this study were: (1) to investigate the decomposition and mineralization of nitroimidazoles (Metronidazole [MNZ], Dimetridazole [DMZ], and Tinidazole [TNZ]) in waste and drinking water using gamma irradiation; (2) to study the decomposition kinetics of these nitroimidazoles;
Jianzhong Shen et al.
Journal of AOAC International, 86(3), 505-509 (2003-07-11)
A liquid chromatographic method was developed for determination of metronidazole (MNZ), ronidazole (RNZ), dimetridazole (DMZ), and 2-hydroxymethyl-1-methyl-5-nitroimidazole (DMZOH) in swine tissue. After extraction with ethyl acetate and evaporation, the nitroimidazoles were redissolved in hydrochloric acid. Hexane was used in the
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