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Sigma-Aldrich

Calcium chloride hexahydrate

tested according to Ph. Eur.

Synonym(s):

Calcii chloridum hexahydricum

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About This Item

Empirical Formula (Hill Notation):
CaCl2 · 6H2O
CAS Number:
Molecular Weight:
219.08
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
NA.21

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

form

solid

mp

30 °C

solubility

H2O: soluble 219.1 g/L at 20 °C

density

1.71 g/mL at 25 °C (lit.)

SMILES string

O.O.O.O.O.O.Cl[Ca]Cl

InChI

1S/Ca.2ClH.6H2O/h;2*1H;6*1H2/q+2;;;;;;;;/p-2

InChI key

QHFQAJHNDKBRBO-UHFFFAOYSA-L

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Application

Calcium chloride hexahydrate has been used as a test compound for measuring the overall activity of low-molecular-weight antioxidants in biological samples by using ′total antioxidative capacity′ inhibition assay.

Biochem/physiol Actions

Calcium chloride act as precipitants during protein crystallization process. It also enhances the competence of Escherichia coli cells in transformation experiments. It strengthen β-lactoglobulin gels by forming crossbridges.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Matthew S Kimber et al.
Proteins, 51(4), 562-568 (2003-06-05)
Protein crystallization is a major bottleneck in protein X-ray crystallography, the workhorse of most structural proteomics projects. Because the principles that govern protein crystallization are too poorly understood to allow them to be used in a strongly predictive sense, the
M Dagert et al.
Gene, 6(1), 23-28 (1979-05-01)
Escherichia coli cells are 4--6 times more transformable and 20--30 times more competent after 24 h incubation in cold calcium chloride than immediately after calcium chloride treatment. With 24-h-old competent cells we obtained routinely 2 . 10(7) transformants per microgram
Livia Saleh et al.
Nature protocols, 5(10), 1627-1634 (2010-10-05)
Aerobic metabolism requires a complex antioxidative system to balance reactive oxygen species (ROS). When in excess, ROS disrupt cellular activities and molecular structures. Owing to the variety of ROS, there are different antioxidative activities that require various tests for their
Tiago Sousa et al.
Journal of pharmaceutical sciences, 103(10), 3171-3175 (2014-08-06)
Azo-bonded prodrugs of 5-aminosalicylic acid (mesalazine)-sulfasalazine, balsalazide, and olsalazine, which are used in the treatment of ulcerative colitis, rely on colonic bacteria to cleave the azo bond and liberate the active drug in the large intestine. The aim of this
Katrien Maes et al.
Journal of chromatography. A, 1360, 217-228 (2014-08-26)
Obtaining maximal sensitivity of nano UHPLC-MS/MS methods is primordial to quantify picomolar concentrations of neuropeptides in microdialysis samples. Since aspecific adsorption of peptides to Eppendorf tubes, pipette tips and UHPLC vials is detrimental for method sensitivity, a strategy is presented

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