SCT051

BioTracker Carbon Monoxide Probe 1 Live Cell Dye

Live cell imaging dye for cellular carbon monoxide (CO), a cell signalling molecule implicated in vasodilation, neurotransmission, anti-inflammatory and anti-apoptotic processes.

• UNSPSC Code: 12352207
• NACRES: NA.47

Properties

• form: lyophilized
• detection method: fluorometric

Description

General description

Carbon Monoxide (CO) is a colorless, odorless, tasteless gas that is highly toxic and lethal to mammals. However, there is growing evidence that CO can be endogenously produced in ourhuman body during the haem catabolism, and it was proved to be an important cell signaling molecule with substantial therapeutic potential protecting from vascular, inflammatory, or even cancer diseases. BioTracker Carbon Monoxide live cell dye is an allyl fluorescein ether-based probe for detecting CO in living cells. The dye is highly selective for CO and shows no effect with other analytes such as F-, Cl-, Br-, I-, AcO-, HCO₃-, N₃-, NO₃-, SO₄^2-, HSO₄-, HSO₃-, HS-, SCN-, CN-, ClO₄-, IO₄-, PO₄^3-, and HPO₄^2-, biothiols such as Cys, Hcy, and GSH, amino acids such as Ser, Trp, Ala,Phe, Gln, Glu, Lys, Leu, Gly, and Ile, and reactive oxygen/nitrogen species (ROS/RNS) such as ClO-, H₂O₂, NO₂-, NO, HNO, ROO-, BuOO-, and -OH.
Spectral Properties:Excitation: 450- 480nm
Emission: 525 nm (Green)
Research Category:Live Cell Dye

Materials Required but Not Supplied:

• PdCl₂ (MilliporeSigma: Cat# 205885-1G or 520659-1G)
• CROM-3 (MilliporeSigma Cat# SML0496-10mg), a carbon monoxide-releasing molecule

Important note: SCT051 staining works only in the presence of CROM-3 and PdCl₂. Refer to product data sheet for more information.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable