MAB80121
Anti-Human Metapneumovirus Antibody, clone 36
clone 36, Chemicon®, from mouse
Synonym(s):
hMPV
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.42
Recommended Products
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
36, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
isotype
IgG2a
shipped in
wet ice
Related Categories
General description
Human metapneumovirus (hMPV) is a member of the pneumovirinae subfamily of paramyxoviruses, first described in 2001 from pediatric respiratory specimens in the Netherlands. It is an enveloped pleomorphic virus with a single negative-strand RNA genome. Two major serotypes, A and B, have been described. Several studies identified hMPV in specimens worldwide, and estimated that by age 5 years 70% of children have developed antibodies to hMPV.
Specificity
Specific to the nuclear protein. Reactive with all sub-types; A1, A2, B1, B2.
Application
Detect Human Metapneumovirus using this Anti-Human Metapneumovirus Antibody, clone 36 validated for use in ELISA, FC & IF.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
Physical form
Format: Purified
Liquid in 0.02M PB with 0.25M NaCl, pH 7.6. Contains 0.1% sodium azide.
Storage and Stability
Store at 2° to 8°C for up to 12 months from date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Kathleen M Nitschinsk et al.
Intervirology, 61(3), 149-154 (2018-08-27)
Human metapneumovirus (hMPV) is an important human respiratory pathogen and is implicated in an array of respiratory illnesses, ranging from asymptomatic infection to severe bronchiolitis. Currently, there is no reliable vaccine or specific antiviral therapy for hMPV infection and treatment
Fernando Villalón-Letelier et al.
mBio, 12(5), e0148421-e0148421 (2021-09-15)
Membrane-associated RING-CH8 (MARCH8) impairs the cell surface expression of envelope glycoproteins from different viruses, reducing their incorporation into virions. Using stable cell lines with inducible MARCH8 expression, we show that MARCH8 did not alter susceptibility to influenza A virus (IAV)
Leah Gillespie et al.
Journal of virology, 90(17), 7848-7863 (2016-06-24)
It is well established that glycosaminoglycans (GAGs) function as attachment factors for human metapneumovirus (HMPV), concentrating virions at the cell surface to promote interaction with other receptors for virus entry and infection. There is increasing evidence to suggest that multiple
Human metapneumovirus associated with respiratory tract infections in a 3-year study of nasal swabs from infants in Italy.
Maggi, Fabrizio, et al.
Journal of Clinical Microbiology, 41, 2987-2991 (2003)
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