ABN478

Anti-LFG Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Protein lifeguard 2, Fas apoptotic inhibitory molecule 2, Neural membrane protein 35, Transmembrane BAX inhibitor motif-containing protein 2, LFG
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: mouse
• species reactivity (predicted by homology): human (immunogen homology)
• technique(s): immunohistochemistry: suitable; western blot: suitable
• UniProt accession no.: Q9BWQ8
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... FAIM2(23017)

Description

General description

Protein lifeguard 2 (LFG) is an antiapoptotic protein belonging to the BI1 family. LFG inhibits the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-death signal. LFG is expressed at high levels in the brain especially in the hippocampus. It is also highly expressed in breast cancer tissues and correlates with the grade of tumor (grade II/grade III) in primary breast tumors.

Immunogen

KLH-conjugated linear peptide corresponding to human LFG.

Application

Detect LFG using this rabbit polyclonal antibody, Anti-LFG Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected LFG in mouse brain tissue.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Quality

Evaluated by Western Blotting in EL4 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected LFG in 15 µg of EL4 cell lysate.

Target description

~35 kDa observed.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
EL4 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable