Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins. LPS 595 (Re) has been shown to stimulate Toll-like receptor-4 (TLR4), but not TLR2, signaling in human cell lines.
Biochem/physiol Actions
Cell permeable: no
Primary Target Stimulate Toll-like receptor-4 (TLR4) signaling in human cell lines
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Harmful (C)
Preparation Note
Warming to 37°C with intermittent vortexing or sonication may be required to achieve complete solubilization in H₂O.
Reconstitution
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months.
Other Notes
Hirschfeld, M., et al. 2000. J. Immunol.165, 618. Tapping, R.I., et al. 2000. J. Immunol.165, 5780. Galanos, C., et al. 1969. Eur. J. Biochem.9, 245.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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