1.02064

Calcium carbonate

precipitated (≤ 0.002% Fe), EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, USP, FCC

• Synonym(s): Calcium carbonate
• Linear Formula: CaCO₃
• CAS Number: 471-34-1
• Molecular Weight: 100.09
• Beilstein: 8008338
• MDL number: MFCD00010906
• UNSPSC Code: 12352302
• EC Index Number: 207-439-9

Properties

• Agency: BP; JP; Ph. Eur.; USP
• Quality Level: 500
• reg. compliance: FCC
• product line: EMPROVE^® ESSENTIAL
• form: solid
• potency: 6450 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH: 9.5-10.5 (20 °C, 100 g/L in H₂O, slurry)
• mp: 825 °C (decomposition)
• density: 2.93 g/mL at 25 °C (lit.)
• application(s): liquid formulation; pharmaceutical; solid formulation
• storage temp.: 2-30°C
• SMILES string: [Ca++].[O-]C([O-])=O
• InChI: 1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2
• InChI key: VTYYLEPIZMXCLO-UHFFFAOYSA-L

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Calcium carbonate is typically used as alkalizer or mineral supplement in solid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable