1.00805

Titanium(IV) oxide

EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, E 171

• Synonym(s): Titanium(IV) oxide, Titanic anhydride, Titanium dioxide
• Empirical Formula (Hill Notation): O₂Ti
• CAS Number: 13463-67-7
• Molecular Weight: 79.87
• MDL number: MFCD00011269
• UNSPSC Code: 12352303
• E Number: E171
• EC Index Number: 236-675-5

Properties

• Agency: BP; ChP; JP; Ph. Eur.; USP
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: fine powder
• particle size: ~0.8 μm (d50)
• pH: 7-8 (20 °C, 100 g/L in H₂O, slurry)
• bp: 2900 °C/1013 hPa
• mp: 1855 °C
• application(s): pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-30°C
• InChI: 1S/2O.Ti
• InChI key: GWEVSGVZZGPLCZ-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Titanium(IV) oxide is a commonly used ingredient in both food and pharmaceuticals. In pharmaceutical applications, Titanium(IV) oxide has been used primarily for solid oral dosage forms as a white pigment.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable