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O3132

Sigma-Aldrich

Oxibendazole

~98%

Synonym(s):

Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15N3O3
CAS Number:
20559-55-1
Molecular Weight:
249.27
EC Number:
243-877-7
MDL number:
MFCD00133728
UNSPSC Code:
12352100
PubChem Substance ID:
57654481
NACRES:
NA.22

Assay

~98%

Quality Level

100

storage temp.

2-8°C

SMILES string

CCCOc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

RAOCRURYZCVHMG-UHFFFAOYSA-N

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Biochem/physiol Actions

Anthelminthic

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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G W Lubega et al.
Biochemical pharmacology, 41(1), 93-101 (1991-01-01)
The low- and high-affinity binding of tritiated benzimidazole anthelmintics (mebendazole and oxibendazole) to tubulin-containing supernatants derived from unembryonated eggs, third stage larvae or adult worms of thiabendazole-susceptible and -resistant strains of Haemonchus contortus were examined and compared. The displacement of
P A Overgaauw et al.
The Veterinary quarterly, 20(2), 69-72 (1998-05-01)
The anthelmintic efficacy and safety of the oxibendazole component in a combination oxibendazole-niclosamide paste were investigated in dogs and cats and in litters of pups with naturally acquired nematode infections. A single dose of 15 mg oxibendazole/kg body weight given
A field evaluation of three methods of administration of anthelminthics to horses.
C Uhlinger et al.
Equine veterinary journal, 24(6), 487-488 (1992-11-01)
S C Tolliver et al.
American journal of veterinary research, 54(6), 908-913 (1993-06-01)
Critical tests were conducted in horses (n = 11) with naturally acquired infections of benzimidazole (BZ)-resistant population-B small strongyles in 1989 and 1990. Anthelmintics administered were thiabendazole (44 mg/kg of body weight, n = 4), oxibendazole (10 mg/kg, n =
C Uhlinger et al.
Journal of the American Veterinary Medical Association, 201(1), 51-55 (1992-07-01)
Anthelmintic schedules that alternate between drug classes are widely used in horses. However, the results of investigations in which ovine nematode parasites were used have established that alternation of drug classes does not delay the development of drug resistance. This
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