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911933

Sigma-Aldrich

Morpholine 3,3,3-trifluoropropanamide

≥95%

Synonym(s):

3,3,3-Trifluoro-1-morpholinopropan-1-one

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About This Item

Empirical Formula (Hill Notation):
C7H10F3NO2
CAS Number:
Molecular Weight:
197.16
MDL number:
UNSPSC Code:
12352101
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Assay

≥95%

form

powder

mp

74-75 °C

storage temp.

2-8°C

Application

Morpholine 3,3,3-trifluoropropanamide, as shown by the Colby lab, gives access to (E)-β-fluoro-α,β-unsaturated amides upon the addition Grignard reagents with high levels of stereo control.

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Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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Related Content

Prof. David Colby's laboratory is developing synthetic methods to enable the efficient modification of complex molecules, such as natural products, as well as the production of fluorinated compounds. They have focused on understanding how to cleave bonds in order to remodel structures, and their first major discovery is that the release of trifluoroacetate is a powerful approach to break carbon–carbon bonds. This strategy has enabled the invention of new reagents and methods for the synthesis of fluorinated products for drug discovery and for exploring medicinal chemistry.

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