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490733

Sigma-Aldrich

Sodium pyruvate-3-13C

99 atom % 13C

Synonym(s):

Pyruvic acid-3-13C sodium salt

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About This Item

Linear Formula:
13CH3COCO2Na
CAS Number:
124052-04-6
Molecular Weight:
111.04
MDL number:
MFCD00084081
UNSPSC Code:
12352106
PubChem Substance ID:
24872596
NACRES:
NA.12

isotopic purity

99 atom % 13C

Quality Level

200

Assay

99% (CP)

form

solid

technique(s)

bio NMR: suitable
mass spectrometry (MS): suitable

mp

>300 °C (lit.)

mass shift

M+1

storage temp.

2-8°C

SMILES string

[Na+].[13CH3]C(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1/i1+1;

InChI key

DAEPDZWVDSPTHF-YTBWXGASSA-M

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General description

Sodium pyruvate-3-13C is an isotopic analogue of sodium pyruvate.

Application

Sodium pyruvate-3-13C is used to study the brain metabolism of exogenous pyruvate.It is also used to investigate the pyruvate metabolism in living cancer cells.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317,H319

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Susana Villa Gonzalez et al.
Journal of neurochemistry, 95(1), 284-293 (2005-09-27)
Pyruvate given in large doses may be neuroprotective in stroke, but it is not known to what degree the brain metabolizes pyruvate. Intravenous injection of [3-13C]pyruvate led to dose-dependent labelling of cerebral metabolites so that at 5 min after injection
Chendong Yang et al.
The Journal of biological chemistry, 289(9), 6212-6224 (2014-01-15)
Metabolic reprogramming facilitates cancer cell growth, so quantitative metabolic flux measurements could produce useful biomarkers. However, current methods to analyze flux in vivo provide either a steady-state overview of relative activities (infusion of (13)C and analysis of extracted metabolites) or

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