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459224

Sigma-Aldrich

(S)-α-Amino-γ-butyrolactone hydrochloride

97%

Synonym(s):

L-Homoserine lactone hydrochloride, HSI

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About This Item

Empirical Formula (Hill Notation):
C4H7NO2 · HCl
CAS Number:
2185-03-7
Molecular Weight:
137.56
Beilstein:
3562187
EC Number:
218-571-1
MDL number:
MFCD00058172
UNSPSC Code:
12352202
PubChem Substance ID:
24869524
NACRES:
NA.22
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Assay

97%

form

powder or crystals

optical activity

[α]20/D −27.8°, c = 1 in H2O

mp

210-220 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Cl.N[C@H]1CCOC1=O

InChI

1S/C4H7NO2.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1

InChI key

XBKCXPRYTLOQKS-DFWYDOINSA-N

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Application

(S)-α-Amino-γ-butyrolactone hydrochloride can be used:
  • As a precursor for the preparation of amino-keto-alcohols and β-amino acids.[1]
  • To prepare N-acylhomoserine lactone (AHL) analogs by reacting with substituted 2-chloro-N-phenylacetamide and different halides.[2]
  • As a starting material for the synthesis of L-discadenine.[3]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKBC9254V
MKBC9254
18911JR
11903EQ

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