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450243
Sodium orthovanadate
99.98% trace metals basis
Synonym(s):
Trisodium vanadate
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About This Item
Linear Formula:
Na3VO4
CAS Number:
Molecular Weight:
183.91
EC Number:
MDL number:
UNSPSC Code:
12161600
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
99.98% trace metals basis
form
solid
reaction suitability
core: vanadium
reagent type: catalyst
mp
850-866 °C (lit.)
SMILES string
[Na+].[Na+].[Na+].[O-][V]([O-])([O-])=O
InChI
1S/3Na.4O.V/q3*+1;;3*-1;
InChI key
IHIXIJGXTJIKRB-UHFFFAOYSA-N
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Application
Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:
- Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.[1]
- Nanorods of vanadium oxide particles by glycothermal method.[2]
- Yttrium vanadate (YVO4) doped with colloidal europium.[3]
Biochem/physiol Actions
An inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases.
Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Customers Also Viewed
Synthesis and characterizations of YVO4: Eu colloids.
Huignard A, et al.
Chemistry of Materials, 14(5), 2264-2269 (2002)
Synthesis and characterization of TM-MCM-48 (TM= Mn, V, Cr) and their catalytic activity in the oxidation of styrene.
Gomez S, et al.
J. Catal., 233(1), 60-67 (2005)
Yu Hasegawa et al.
The Journal of pharmacology and experimental therapeutics, 317(2), 875-881 (2006-02-08)
Vanadium is widely distributed in the environment and exhibits various biological and physiological effects in the human body. We previously documented the neuroprotective effect of sodium orthovanadate (SOV) against in rodents i.v. injected with 2 ml/kg 50 mM SOV just
Glycothermal synthesis of assembled vanadium oxide nanostructures for gas sensing.
Fu H, et al.
Journal of Nanoparticle Research, 14(6), 871-871 (2012)
A Morita et al.
Cell death and differentiation, 13(3), 499-511 (2005-09-03)
We previously reported that p42/SETbeta is a substrate for caspase-7 in irradiated MOLT-4 cells, and that treating the cells with sodium orthovanadate (vanadate) inhibits p42/SETbeta's caspase-mediated cleavage. Here, we initially found that the inhibitory effect of vanadate was due to
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What is the Department of Transportation shipping information for this product?
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What is Product 450243, Sodium orthovanadate, typically used for?
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This product can be used as a catalyst in chemical synthesis. It also utilized as an inhibitor of ATPase, alkaline phosphatase and tyrosine phosphatase.
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What is the solubility of Product 450243, sodium orthovandate, and how do I store the solution?
1 answer-
Solutions prepared as 1 mM in water (or higher if desired) and adjusted to pH 10 can be aliquotted in plastic tubes and stored at -20°C. To ensure the presence of monomers, solutions should be heated to boiling until translucent and pH re-adjusted to 10.
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For Product 450243, Sodium orthovanadate, what does metal basis purity mean?
1 answer-
This product's purity is determined by ICP analysis. Trace metal impurities are analyzed, quantified and reported on the certificate of analysis for each lot/batch of product. The total metallic impurities are subtracted from 100% to result in the purity percentage based on metals.
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