394580

Myristic anhydride

95%

• Synonym(s): Tetradecanoic anhydride
• Linear Formula: [CH₃(CH₂)₁₂CO]₂O
• CAS Number: 626-29-9
• Molecular Weight: 438.73
• EC Number: 210-941-0
• MDL number: MFCD00056151
• UNSPSC Code: 12352100
• PubChem Substance ID: 24864606
• NACRES: NA.22

Properties

• Assay: 95%
• form: solid
• mp: 53-55 °C (lit.)
• SMILES string: CCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCC
• InChI: 1S/C28H54O3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27(29)31-28(30)26-24-22-20-18-16-14-12-10-8-6-4-2/h3-26H2,1-2H3
• InChI key: RCRYHUPTBJZEQS-UHFFFAOYSA-N

Description

General description

Myristic anhydride is an anhydride of myristic acid. Its synthesis by reacting myristoyl chloride with acetic anhydride has been reported. It participates in the synthesis of fatty acyl derivatives of macrocyclic peptides.

Application

Myristic anhydride may be used in the following studies:

• As a reactant to synthesize cholesteryl myristate by reacting with cholesterol.
• As a reactant in the synthesis of 1,2-dimyristoyl-sn-glycero-3-phosphocholine by acylating sn-glycero-3-phosphocholine.
• As a reagent in the synthesis of 3-(bis-{2-(tert-butyldimethylsilyloxy)ethyl}amino)propane-1,2-diol, an intermediate of cationic lipid.
• As a reactant to synthesize neryl myristate by reacting with nerol.
• As a reagent to synthesize myristoylated t-butylglutamic acid by myristoylation of γ-tert-butoxy-glutamic acid.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves