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334227

Sigma-Aldrich

4-Chloro-2-fluorophenol

99%

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About This Item

Linear Formula:
ClC6H3(F)OH
CAS Number:
Molecular Weight:
146.55
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

99%

form

liquid

refractive index

n20/D 1.536 (lit.)

bp

103-104 °C/50 mmHg (lit.)

mp

20 °C (lit.)

density

1.378 g/mL at 25 °C (lit.)

functional group

chloro
fluoro

SMILES string

Oc1ccc(Cl)cc1F

InChI

1S/C6H4ClFO/c7-4-1-2-6(9)5(8)3-4/h1-3,9H

InChI key

ZKMUKBBWORLNLA-UHFFFAOYSA-N

General description

4-Chloro-2-fluorophenol undergoes reductive dechlorination to yield 2-fluorophenol by the sulfate-reducing consortium.

Application

4-Chloro-2-fluorophenol was used in the enzymatic preparation of 5-chloro-3-fluorocatechol.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

177.8 °F - closed cup

Flash Point(C)

81 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Reductive dechlorination of halogenated phenols by a sulfate-reducing consortium.
Haggblom MM.
FEMS Microbiology Ecology, 26(1), 35-41 (1998)
Inna P Solyanikova et al.
Applied and environmental microbiology, 69(9), 5636-5642 (2003-09-06)
The present study describes the (19)F nuclear magnetic resonance analysis of the conversion of 3-halocatechols to lactones by purified chlorocatechol 1,2-dioxygenase (ClcA2), chloromuconate cycloisomerase (ClcB2), and chloromuconolactone dehalogenase (ClcF) from Rhodococcus opacus 1cp grown on 2-chlorophenol. The 3-halocatechol substrates were

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