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26253

Sigma-Aldrich

(3-Chloropropyl)trimethylsilane

≥97.0%

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About This Item

Empirical Formula (Hill Notation):
C6H15ClSi
CAS Number:
2344-83-4
Molecular Weight:
150.72
Beilstein:
1732625
EC Number:
219-059-0
MDL number:
MFCD00045299
UNSPSC Code:
12352100
PubChem Substance ID:
57648158
NACRES:
NA.22
Assay:
≥97.0%
Pricing and availability is not currently available.

Assay

≥97.0%

refractive index

n20/D 1.431

bp

151 °C (lit.)

density

0.878 g/mL at 20 °C (lit.)

functional group

chloro

SMILES string

C[Si](C)(C)CCCCl

InChI

1S/C6H15ClSi/c1-8(2,3)6-4-5-7/h4-6H2,1-3H3

InChI key

QXDDDCNYAAJLBT-UHFFFAOYSA-N

Application

(3-Chloropropyl)trimethylsilane has been used in the preparation of:
  • 8-(3-trimethylsilylpropoxy)quinolone under phase transfer catalytic conditions[1]
  • 5-trimethylsilyl pentanol[2]
  • N-(tri-methylsilylalkyl)diamines[3]

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

120.2 °F - closed cup

Flash Point(C)

49 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBR4469V
BCBM4986V
BCBF3398V
434649/1
410108/1

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New deoxynojirimycin derivatives as potent inhibitors of intestinal a-glucohydrolases.
Lesur B, et al.
Bioorganic & Medicinal Chemistry Letters, 7(3), 355-360 (1997)
Organosilicon Compounds. Part V. Synthesis of N-(trimethylsilylalkyl) diamines and N-(trimethylsilylalkyl)-N'-(2-mercaptoethyl) diamines.
Thames SF and Edwards LH.
J. Chem. Soc. Sect. C, 2339-2342 (1968)
Silyl Modification of Biologically Active Compounds. 10. Lipid Type Organosilicon Derivatives of 8-Hydroxyquinoline and N-(2-Hydroxyethyl)-1, 2, 3, 4-tetrahydro (sila, iso) quinolines.
Segal I, et al.
Chemistry of Heterocyclic Compounds, 41(5), 613-624 (2005)

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