144908

2-Amino-4-methylphenol

97%

• Synonym(s): 2-Amino-p-cresol, 2-Hydroxy-5-methylaniline, 3-Amino-4-hydroxytoluene
• Linear Formula: H₂NC₆H₃(CH₃)OH
• CAS Number: 95-84-1
• Molecular Weight: 123.15
• Beilstein: 606494
• EC Number: 202-457-3
• MDL number: MFCD00007699
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848690
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• mp: 133-136 °C (lit.)
• SMILES string: Cc1ccc(O)c(N)c1
• InChI: 1S/C7H9NO/c1-5-2-3-7(9)6(8)4-5/h2-4,9H,8H2,1H3
• InChI key: ZMXYNJXDULEQCK-UHFFFAOYSA-N

Description

General description

2-Amino-4-methylphenol is the major sensitizer in contact allergy to Disperse Yellow 3[1]. It reacts with acetylacetone in absolute ethanol to yield 4-(2-hydroxy-5-methylphenyl)imino-2-pentanone[2]. It was converted to dihydrophenoxazinone by purified human hemoglobin[3].

Application

2-Amino-4-methylphenol was used in the synthesis of novel functionalized spiropyran derivatives of 2H-1,3-benzoxazinone series[4].

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves