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D-Val-Leu-Lys 4-nitroanilide dihydrochloride

Name: <SC>D</SC>-Val-Leu-Lys 4-nitroanilide dihydrochloride
Brand: SIGMA

plasmin substrate

Synonym(s):

D-Val-Leu-Lys-pNA dihydrochloride, D-Valyl-L-leucyl-L-lysine 4-nitroanilide dihydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₃₈N₆O₅ · 2HCl

CAS Number:

62354-43-2

Molecular Weight:

551.51

NACRES:

NA.32

PubChem Substance ID:

24900701

UNSPSC Code:

12352204

MDL number:

MFCD00077899

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Properties

Quality Segment

200

assay

≥98% (TLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless to yellow

storage temp.

−20°C

SMILES string

Cl.Cl.CC(C)C[C@H](NC(=O)[C@H](N)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C23H38N6O5.2ClH/c1-14(2)13-19(28-23(32)20(25)15(3)4)22(31)27-18(7-5-6-12-24)21(30)26-16-8-10-17(11-9-16)29(33)34;;/h8-11,14-15,18-20H,5-7,12-13,24-25H2,1-4H3,(H,26,30)(H,27,31)(H,28,32);2*1H/t18-,19-,20+;;/m0../s1

InChI key

VESQMNNSPPEOSZ-ZLARAOTRSA-N

Description

Application

D-Val-Leu-Lys 4-nitroanilide dihydrochloride has been used as a chromogenic substrate to determine the formation of plasmin from plasminogen in amidolytic activity assay[1] and plasminogen activating assay.[2]

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This Item	V7127	T6140	M4765
Sigma-Aldrich V0882 D-Val-Leu-Lys 4-nitroanilide dihydrochloride	Sigma-Aldrich V7127 D-Val-Leu-Lys p-nitroanilide dihydrochloride	Sigma-Aldrich T6140 N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt	Sigma-Aldrich M4765 N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide
assay ≥98% (TLC)	assay ≥98% (HPLC)	assay ≥98% (TLC)	assay ≥98% (HPLC)
solubility water: 50 mg/mL, clear, colorless to yellow	solubility water: 50 mg/mL, clear, light yellow	solubility ethanol: 50 mg/mL, colorless to yellow	solubility DMF: soluble 25 mg/mL, clear, colorless to light yellow
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 300
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302 + H312 + H332,H315,H319,H335,H361

pcodes

P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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