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Y0000481

Dibrompropamidine for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dibrompropamidine diisetionate

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About This Item

Empirical Formula (Hill Notation):
C21H30Br2N4O10S2
CAS Number:
Molecular Weight:
722.42
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

dibrompropamidine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C17H18Br2N4O2.C2H6O4S/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19;3-1-2-7(4,5)6/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23);3H,1-2H2,(H,4,5,6)

InChI key

BZACJASHKPPTKX-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dibrompropamidine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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R M Richards et al.
Journal of pharmaceutical sciences, 80(9), 861-867 (1991-09-01)
Modifications of antibacterial activity have been demonstrated using combinations of two antibacterials from trimethoprim, sulfonamides (sulfadiazine, sulfamerazine, and silver sulfadiazine), silver nitrate, and dibromopropamidine isethionate, either formulated in a cream base or dissolved in peptone water. The creams were evaluated
Allergic contact dermatitis from dibrompropamidine cream.
C Lützow-Holm
Contact dermatitis, 20(2), 160-160 (1989-02-01)
Cosmetic contact lens-related Acanthamoeba keratitis.
James McKelvie et al.
Clinical & experimental ophthalmology, 37(4), 419-420 (2009-07-15)
P Wright et al.
The British journal of ophthalmology, 69(10), 778-782 (1985-10-01)
The first medical cure of a corneal infection due to an Acanthamoeba species is reported. The 44-year-old patient developed a suppurative keratitis associated with an epithelial defect, hypopyon, and secondary glaucoma. Acanthamoeba was confirmed as the causative agent four months
S S Asghar et al.
Biochimica et biophysica acta, 317(2), 539-548 (1973-08-30)
A series of amidino compounds has been investigated for their inhibitory effects on C1s, C1r, and generation of C1s. Diamidines consisting of two amidinophenyl residues linked in para position by a molecular bridge proved to be the strongest competitive inhibitors

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