32097

Etoricoxib

VETRANAL^®, analytical standard

• Synonym(s): 5-Chloro-3-[4-(methylsulfonyl)phenyl]-2-(2-methyl-5-pyridinyl)pyridine, 5-Chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-2,3′-bipyridine
• Empirical Formula (Hill Notation): C₁₈H₁₅ClN₂O₂S
• CAS Number: 202409-33-4
• Molecular Weight: 358.84
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329753738
• MDL number: MFCD06797512
• Beilstein/REAXYS Number: 8073797

Properties

• grade: analytical standard
• Quality Segment: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC1=NC=C(C2=C(C3=CC=C(S(C)(=O)=O)C=C3)C=C(Cl)C=N2)C=C1
• InChI: 1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3
• InChI key: MNJVRJDLRVPLFE-UHFFFAOYSA-N
• Gene Information: human ... PTGS2(5743)

Description

General description

Etoricoxib is a non-steroidal cyclooxygenase-2 (COX-2) selective anti-inflammatory drug mostly used to treat patients suffering from osteoarthritis and rheumatoid arthritis.

Application

Etoricoxib may have been used as reference standard in liquid chromatography-tandem mass spectrometry method with atmospheric pressure chemical ionization (LC-APCI/MS/MS) method for determination of etoricoxib from human plasma.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Codes: H302,H310
• Precautionary Statements: P262 - P264 - P270 - P280 - P301 + P312 - P302 + P352 + P310
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 4 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3