860626P

C8 Dihydroceramide (d18:0/8:0)

Avanti Research^™ - A Croda Brand 860626P, powder

• Synonym(s): N-octanoyl-D-erythro-sphinganine
• Empirical Formula (Hill Notation): C₂₆H₅₃NO₃
• CAS Number: 145774-33-0
• Molecular Weight: 427.70
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 5 mg (860626P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 860626P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
• InChI: 1S/C26H53NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h24-25,28-29H,3-23H2,1-2H3,(H,27,30)/t24-,25+/m0/s1
• InChI key: LGOFBZUQIUVJFS-LOSJGSFVSA-N

Description

Application

C8 Dihydroceramide (d18:0/8:0) has been used as an internal standard to quantify the lipid extracted from human plasma by liquid chromatography mass spectrometry during high-throughput plasma lipidomics.

Biochem/physiol Actions

C8 Dihydroceramide (d18:0/8:0) or N-octanoyl-D-erythro-sphinganine, is a synthetic dihydroceramide. Dihydroceramide acts as a precursor for de-novo ceramide synthesis. C8 Dihydroceramide mimics γ-tocotrienol (γTE) in stimulating NF-κB-target protein A20 expression, increasing endoplasmic reticulum (ER) stress and reducing tumor necrosis factor (TNF)-triggered nuclear factor kappa B (NF-κB) activation.

Packaging

5 mL Amber Glass Screw Cap Vial (860626P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3