917575
PhotoCol™-IRG, methacrylated collagen bioink kit, with Irgacure
Synonym(s):
3D Bioprinting, Bioink, Collagen
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352201
NACRES:
NA.23
Recommended Products
description
Methacrylated collagen:
Degree of methacrylation ≥ 20%
Product components :
Methacrylated collagen (100 mg)
20 mM acetic acid (50 mL)
Neutralization solution (10 mL)
Irgacure photoinitiator ( 100 mg)
Quality Level
sterility
sterile; sterile-filtered
impurities
≤10 EU/mL Endotoxin
storage temp.
2-8°C
Application
PhotoCol™-IRG bioink kit consists of purified methacrylated Type I bovine collagen as the core component with other support reagents. The methacrylated Type I collagen is produced from telo-peptide intact bovine collagen where the collagen has been modified by reacting the free amines, primarily the ε-amines groups of the lysine residues as well as the a-amines groups on the N-termini. Over 20% of the total lysine residues of the collagen molecule have been methacrylated. A bottle of 20 mM acetic acid solution is provided to solubilize the lyophilized methacrylated collagen at concentrations ranging from 3 to 8 mg/ml. The neutralization solution consists of an alkaline 10X phosphate buffered saline (PBS) solution which provides physiological salts and pH in the final mixture. The photoinitiator consists of Irgacure 2959 to be formulated in methanol (methanol not included), which allows UV crosslinking of the printed structure at 365 nm. PhotoCol™-IRG provides native-like 3D collagen gels, and the final gel stiffness can be customized by changing collagen concentrations and crosslinking.
Legal Information
PhotoCol is a trademark of Advanced BioMatrix, Inc.
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2
Storage Class Code
10 - Combustible liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
A New Approach to Design Artificial 3D Microniches with Combined Chemical, Topographical, and Rheological Cues.
Stoecklin C, et al.
Advanced Biosystems (2018)
Andrea Mazzocchi et al.
Biofabrication, 11(1), 015003-015003 (2018-10-03)
Current 3D printing of tissue is restricted by the use of biomaterials that do not recapitulate the native properties of the extracellular matrix (ECM). These restrictions have thus far prevented optimization of composition and structure of the in vivo tissue
Ian D Gaudet et al.
Biointerphases, 7(1-4), 25-25 (2012-05-17)
Type-I collagen is an attractive scaffold material for tissue engineering due to its ability to self-assemble into a fibrillar hydrogel, its innate support of tissue cells through bioactive adhesion sites, and its biodegradability. However, a lack of control of material
Andrea Mazzocchi et al.
ACS biomaterials science & engineering, 5(4), 1937-1943 (2019-11-15)
Lung cancer is the leading cause of cancer-related death worldwide yet in vitro disease models have been limited to traditional 2D culture utilizing cancer cell lines. In contrast, recently developed 3D models (organoids) have been adopted by researchers to improve
Abigail Isaacson et al.
Experimental eye research, 173, 188-193 (2018-05-18)
Corneal transplantation constitutes one of the leading treatments for severe cases of loss of corneal function. Due to its limitations, a concerted effort has been made by tissue engineers to produce functional, synthetic corneal prostheses as an alternative recourse. However
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service