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Sigma-Aldrich

Poly(allylamine hydrochloride)

average Mw ~17,500 (GPC vs. PEG std.)

Synonym(s):

PAA HCl, PAH

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About This Item

Linear Formula:
[CH2CH(CH2NH2 · HCl)]n
CAS Number:
71550-12-4
EC Number:
415-050-2
MDL number:
MFCD00084396
UNSPSC Code:
12162002
PubChem Substance ID:
24857093
NACRES:
NA.23

form

solid

mol wt

average Mw ~17,500 (GPC vs. PEG std.)

SMILES string

Cl.NCC=C

InChI

1S/C3H7N/c1-2-3-4/h2H,1,3-4H2

InChI key

VVJKKWFAADXIJK-UHFFFAOYSA-N

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General description

Poly(allylamine hydrochloride) (PAH) is a water-soluble weak-base and a biodegradable polymer.

Application

Poly(allylamine hydrochloride) can be used as a starting material to prepare:
  • Chitosan/PAH polymer blend films by solution casting technique. These films can be employed in injectable drug delivery systems and tissue generation.
  • Cross-linked amino-modified graphene oxide for the removal of Cr(IV) from aqueous solutions.
  • Polyelectrolyte multilayers(PEMs) by the layer-by-layer method. These PEMs can be used to prepare controlled drug delivery systems and coatings with controlled cell adhesion properties.
Used to make redox hydrogel-modified electrodes for measuring enzyme responses.

Features and Benefits

  • Excellent environmental stability
  • Water-soluble
  • Low cost

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gold nanoparticles functionalized with doxorubicin and stabilized with multilayers of degradable polyelectrolyte were allowed to age in aqueous medium in vitro in order to show the possibility of drug release in cellular environment. The chemico-physical characteristics of the nanoparticles are
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Expert opinion on drug delivery, 9(10), 1197-1207 (2012-09-27)
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The patterned template-assisted assembly of the cubic microparticles driven by the competing capillary, Columbic, and van der Waals forces had been studied in comparison with the traditional spherical colloidal microparticles. We observed that the spherical and cubic microparticles assembled with
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Layer-by-Layer (LbL) Assembly, A "Gentle Yet Flexible" Method Toward Functional Biomaterials

Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the mild, yet adaptable LbL technique.

Polyelectrolyte Multilayer Films and Membrane Functionalization

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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