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47864

Nicotinic acid

analytical standard

Synonym(s):

3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B3

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About This Item

Linear Formula:
NC5H4CO2H
CAS Number:
Molecular Weight:
123.11
EC Number:
200-441-0
UNSPSC Code:
12164500
PubChem Substance ID:
Beilstein/REAXYS Number:
109591
MDL number:
NACRES:
NA.24
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grade

analytical standard

Quality Segment

CofA

current certificate can be downloaded

feature

standard type water soluble vitamin

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

236-239 °C (lit.)

density

1.473 g/cm3 at 25 °C

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-30°C

SMILES string

OC(=O)c1cccnc1

InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)
rat ... Chrnb2(54239)

General description

Nicotinic acid acts as an antilipolytic drug in adipose tissue, and is commonly used for hyperlipoproteinaemia and pellagra.
Nicotinic acid is a water soluble, vitamin belonging to B complex group of vitamins, which can be used as a broad spectrum lipid lowering drug. Its mode of action basically involves the inhibition of the hormone-sensitive triglyceride lipase and thereby, decreasing the lipolysis in adipose tissue.

Application

Nicotinic acid may be used as an analytical reference standard for the quantification of the analyte in tablet dosage forms using reversed-phase high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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This Item
N0761N412672309
description

analytical standard

description

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥98%

description

≥98%

description

≥99.5% (HPLC)

grade

analytical standard

grade

-

grade

-

grade

-

format

neat

format

-

format

-

format

-

packaging

ampule of 1000 mg

packaging

-

packaging

-

packaging

-

CofA

current certificate can be downloaded

CofA

-

CofA

-

CofA

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

mp

236-239 °C (lit.)

mp

236-239 °C (lit.)

mp

236-239 °C (lit.)

mp

234-238 °C, 236-239 °C (lit.)


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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

379.4 °F - closed cup

Flash Point (°C)

193 °C - closed cup

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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Certificates of Analysis (COA)

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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. questo standard è certificato iso17034 o iso 17025?

    1 answer
    1. Analytical standards are not ISO 17025 or 17034 certified. This level of certification is for a certified reference material such as product PHR1276.

      https://www.sigmaaldrich.com/product/sial/phr1276

      Helpful?

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