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TTR002

Sigma-Aldrich

Amyloid TISSUE-TROL Control Slides

from human heart

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About This Item

UNSPSC Code:
41116121
NACRES:
NA.47

biological source

human heart

application(s)

hematology
histology

storage temp.

room temp

General description

Amyloid TISSUE-TROL Control Slides are histology slides embedded with human heart tissue. The embedded heart tissue is embedded in paraffin and contains Amyloid proteins. The product comes with one reference slide stained using Congo Red (amyloid stain). Historically, amyloids have been described as fibrillar protein deposits often associated with a disease. Disease caused by amyloids are referred to as “amyloidosis”.

Application

Amyloid TISSUE-TROL Control Slides is used as a positive control to study pancreatic inflammation.

Components

Box contains 24 unstained slides plus one reference slide stained using Amyloid Stain, Congo Red (Procedure No. HT60).

Legal Information

TISSUE-TROL is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J C Rochet et al.
Current opinion in structural biology, 10(1), 60-68 (2000-02-19)
Recent progress has improved our knowledge of how proteins form amyloid fibrils. Both 'natively unfolded' and globular proteins have been shown to initiate fibrillization by adopting a partially structured conformation. Oligomeric prefibrillar intermediates have been extensively characterized with respect to
Pancreatic inflammation and increased islet macrophages in insulin resistant juvenile primates.
Nicol L, et al.
The Journal of Endocrinology, JOE-J12 (2013)
L E Nicol et al.
The Journal of endocrinology, 217(2), 207-213 (2013-02-20)
Chronic high caloric intake has contributed to the increased prevalence of pediatric obesity and related morbidities. Most overweight or obese children, however, do not present with frank metabolic disease but rather insulin resistance or subclinical precursors. The innate immune system

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