T8877

2,3,5-Triphenyltetrazolium chloride

≥98.0% (HPLC)

• Synonym(s): TPTZ, TTZ, Tetrazolium Red
• Empirical Formula (Hill Notation): C₁₉H₁₅ClN₄
• CAS Number: 298-96-4
• Molecular Weight: 334.80
• UNSPSC Code: 12171500
• NACRES: NA.47
• PubChem Substance ID: 24900566
• EC Number: 206-071-6
• Beilstein/REAXYS Number: 3923356
• MDL number: MFCD00011963

Properties

• Quality Segment: 200
• assay: ≥98.0% (HPLC)
• form: powder
• color: faintly yellow
• solubility: H₂O: 50 mg/mL
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: 2-8°C
• SMILES string: [Cl-].c1ccc(cc1)-c2nn(-c3ccccc3)[n+](n2)-c4ccccc4
• InChI: 1S/C19H15N4.ClH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H;1H/q+1;/p-1
• InChI key: PKDBCJSWQUOKDO-UHFFFAOYSA-M

Description

General description

2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.

Application

2,3,5-Triphenyltetrazolium chloride has been used to stain heart tissue to measure the extent of acute lesion. It has also been used to stain brain tissue to check the size of infarct area.

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H228,H315,H319
• pcodes: P210 - P240 - P241 - P264 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2
• Storage Class: 4.1B - Flammable solid hazardous materials
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves