Key Documents

View All Documentation

Trypsin from human pancreas

Name: Trypsin from human pancreas
Brand: SIGMA

salt-free, lyophilized powder, vial of ≥1,000 BAEE units

Synonym(s):

Serine Protease 1

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

CAS Number:

9002-07-7

UNSPSC Code:

12352204

NACRES:

NA.54

EC Number:

232-650-8

MDL number:

MFCD01323069

EC Number:

3.4.21.4 (BRENDA, IUBMB)

Biological source:

human pancreas

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

human pancreas

Quality Segment

200

form

salt-free, lyophilized powder

packaging

vial of ≥1,000 BAEE units

UniProt accession no.

P07477, P07478, P35030

storage temp.

−20°C

Gene Information

human ... PRSS1(5644), PRSS2(5645), PRSS3(5646)

Description

General description

The trypsin molecule has two domains: one is related to the enzyme active site and the tryptophan residues; the other is related to the 8-anilinonaphthalene-1-sulfonate binding.

Trypsin is a serine protease. The pancreas produce the precursor trypsinogen and secretes it to the intestine. Trypsinogen is converted to trypsin by enterokinase in the intestinal mucous membrane.

Application

Trypsin has been used in a study to assess the similarities between the hepatitis E virus and human astrovirus. [1] Trypsin has also been used in a study to characterize a unique technique for culturing primary adult human epithelial progenitor, or stem, cells. [2]

Preparation Note

Minimum 1,000 BAEE units/vial

Analysis Note

Protein determined by E1%/280.

Other Notes

One BAEE unit will produce a ΔA₂₅₃ of 0.001 per min at pH 7.6 at 25 °C using BAEE as substrate. Reaction volume = 3.2 mL (1 cm light path).

View more information on trypsin at www.sigma-aldrich.com/enzymeexplorer

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	T4799	T7409	T5266
Sigma-Aldrich T6424 Trypsin from human pancreas	Sigma-Aldrich T4799 Trypsin from porcine pancreas	Sigma-Aldrich T7409 Trypsin from porcine pancreas	Sigma-Aldrich T5266 Trypsin from porcine pancreas
description salt-free, lyophilized powder, vial of ≥1,000 BAEE units	description lyophilized powder, BioReagent, suitable for cell culture, 1,000-2,000 BAEE units/mg solid	description lyophilized powder, Type II-S, 1,000-2,000 units/mg dry solid	description lyophilized powder, γ-irradiated, BioXtra, suitable for cell culture, 1,000-2,000 BAEE units/mg solid
Gene Information human ... PRSS1(5644), PRSS2(5645), PRSS3(5646)	Gene Information -	Gene Information -	Gene Information -
biological source human pancreas	biological source Porcine pancreas	biological source -	biological source Porcine pancreas
form salt-free, lyophilized powder	form lyophilized powder	form lyophilized powder	form lyophilized powder
UniProt accession no. P07477, P35030, P07478	UniProt accession no. -	UniProt accession no. -	UniProt accession no. -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
packaging vial of ≥1,000 BAEE units	packaging -	packaging -	packaging -

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H315,H319,H334,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.