T2943
Tissue plasminogen activator chromogenic substrate
≥95% (HPLC), solid
Synonym(s):
TPA Activity Assay
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About This Item
Quality Level
assay
≥95% (HPLC)
form
solid
mol wt
apparent mol wt 658.9
solubility
methanol: water (1:9): 25 mg/mL
storage temp.
2-8°C
General description
Tissue plasminogen activator chromogenic substrate is a highly sensitive chromogenic peptide substrate for tissue plasminogen activator (tPA). It shows different sensitivity to native single-chain tPA (sc-tPA) and its fully active two-chain form (tc-tPA).
Application
Tissue plasminogen activator chromogenic substrate has been used:
- in tissue plasminogen activator inhibition assay
- to determine the plasminogen activator (PA) activity by studying the glycosylation properties of tissue plasminogen activator (tPA) activities in effusions using concanavalin A-Sepharose (conA-S) chromatography
- in inhibition assays and complex formation analyses of wild type (WT) neuroserpin (NS) and its variants
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
Mahdieh Bayat et al.
Journal of biotechnology, 280, 1-10 (2018-05-29)
The aim of the present study was to investigate the effect of three routine drug excipients, as osmolytes, in three different concentrations, on structure, thermal stability and the activity of single-chain (sc-) tenecteplase. To see the influence of trehalose, mannitol
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Organic osmolytes, as major cellular compounds, cause protein stabilization in the native form. In the present study, the possible chaperone effects of the three naturally occurring osmolytes on the two-chain form of tenecteplase (tc-TNK), a recombinant, genetically engineered mutant tissue
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T2943-25MG | 04061832926841 |