SRP4145

IL-6 from rat

recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC)

• Synonym(s): B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, IFN-b2, MGI-2
• UNSPSC Code: 12352202
• NACRES: NA.32
• MDL number: MFCD01323739

Properties

• biological source: rat
• recombinant: expressed in E. coli
• assay: ≥90% (HPLC), ≥90% (SDS-PAGE)
• form: lyophilized
• potency: <0.01 ng/mL ED₅₀
• mol wt: ~21.7 kDa
• packaging: pkg of 10 μg
• impurities: endotoxin, tested
• NCBI accession no.: P20607
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: rat ... Il6(24498)

Description

General description

Interleukin- 6 (IL-6) is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is a pro-inflammatory cytokine. IL-6 originates from mononuclear phagocytes, T and B lymphocytes, vascular endothelial cells and fibroblasts. It has a role in various physiological and pathological processes. IL-6 plays an important role in intracellular signaling pathways. Recombinant rat IL-6 is a 21.7kDa protein containing 187 amino acid residues.

Physical form

Lyophilized without any additives.

Preparation Note

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in 10 mM HCl to a concentration of 0.1-1.0 μg/μL. The solution can then be diluted into other aqueous buffers.