SML3638

Ceftobiprole

≥95% (HPLC), Cell wall synthesis inhibitor, powder

• Synonym(s): (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-ylidene)- 2-nitroso-1-oxoethyl]amino]-8-oxo-3-[(E)-[2-oxo-1-[(3R)- 3-pyrrolidinyl]-3-pyrrolidinylidene]methyl]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, BAL 9141, BAL 9141-000, Ro 63-9141
• Empirical Formula (Hill Notation): C₂₀H₂₂N₈O₆S₂
• CAS Number: 209467-52-7
• Molecular Weight: 534.57
• UNSPSC Code: 51111800
• NACRES: NA.25
• MDL number: MFCD25976436
• Assay: ≥95% (HPLC)
• Form: powder

Properties

• Product Name: Ceftobiprole, ≥95% (HPLC)
• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (Acidified)
• storage temp.: -10 to -25°C
• SMILES string: [s]1nc(nc1N)C(N=O)C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)\C=C4/CCN(C/4=O)[C@H]5CNCC5
• InChI: 1S/C20H22N8O6S2/c21-20-24-14(26-36-20)11(25-34)15(29)23-12-17(31)28-13(19(32)33)9(7-35-18(12)28)5-8-2-4-27(16(8)30)10-1-3-22-6-10/h5,10-12,18,22H,1-4,6-7H2,(H,23,29)(H,32,33)(H2,21,24,26)/b8-5+/t10-,11?,12-,18-/m1/s1
• InChI key: XLHWFEHWWUCKOL-ADPMQJGOSA-N

Description

Biochem/physiol Actions

Broad-spectrum cephalosporin active against MRSA

Ceftobiprole is a fifth generation broad spectrum cephalosporin that is active against many resistant bacterial strains including methicillin-resistant Staphylococcus aureus (MRSA). Ceftobiprole inhabits PBP1 (penicillin-binding protein 1), PBP2 and ß-lactam resistance determinant PBP2a.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable